Sensitivity and specificity of optic disc variables and analysis of a new variable (MP/D) for glaucoma diagnosis with the Glaucoma-Scope
a Glaucoma
Institute, Saint Joseph Hospital Foundation, Paris, France, b Department of Ophthalmology, Rothschild Eye
Foundation, Paris, France
Correspondence to: Yves Lachkar, Glaucoma Institute, Saint Joseph Hospital Foundation, 3 ter rue Pierre Larousse, Paris 75014, France.
Accepted for publication 26 June 1997
AIM
In an attempt to use the quantitative optic
disc measurements of the Glaucoma-Scope (OIS Sacramento, CA, USA)
to distinguish glaucomatous from normal optic discs, a new variable was
investigated, the mean disc corrected for the disc size by dividing by
the disc area: MP/D.
METHODSGlaucoma-Scope disc evaluation was
performed on 81 eyes of 51 patients split into the following groups
based on Humphrey 24-2 visual field and clinical criteria of glaucoma:
chronic glaucoma n=27 (including only early, n=17, and low tension
glaucoma, n=10), ocular hypertension n=24, pseudoglaucomatous large
discs, n=12, and normal eyes, n=18. Classic optic disc variables (the
vertical and horizontal c/d ratios, and the c/d area) were compared
with the new MP/D index calculating receiver operating characteristic curves.
RESULTSThe MP/D ratio was able to identify the
glaucomatous eyes more easily than other ratios. Areas under the curves
were: 0.91 (MP/D); 0.87 (c/d area); 0.85 (c/d vertical); and 0.80 (c/d horizontal). The MP/D index was also correlated with the mean
deviation (r=0.466; p=0.001).
CONCLUSIONMP/D may prove useful in detecting
glaucomatous optic nerve damage and could be an interesting screening
tool for primary open angle glaucoma.
© 1997 by British Journal of Ophthalmology
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