Intraocular pressure and central visual field of normal tension glaucoma
Department of Ophthalmology, University of Tokyo School
of Medicine, Tokyo, Japan
Correspondence to: Makoto Araie, MD, Department of Ophthalmology, University of Tokyo School of Medicine, 7-3-1, Hongo, Bunkyo-ku, Tokyo, 113, Japan.
Accepted for publication 26 June 1997
AIM
To study whether damage in the central 30°
field of normal tension glaucoma (NTG) is relatively heterogeneous or
homogeneous with respect to intraocular pressure (IOP) related damage.
METHODSUsing the results of Humphrey perimeter
examinations, the central 30° field was divided into four subfields;
superior and inferior hemifields excluding the caecocentral field (30-2 program) and superior and inferior 10° hemifields (10-2 program). In
103 NTG cases, the intraindividual bilateral difference in the mean of
total deviations (mean TD) in the four subfields was analysed by
multiple linear regression to correct the effects of factors other than
IOP. Explanatory variables were the intraindividual bilateral
difference in the mean of clinic IOP (IOPmean), that in the
ratio of area of peripapillary atrophy corresponding to each subfield
to disc area, and that in myopic refraction.
RESULTSThe intraindividual bilateral difference
in the mean TD was significantly and negatively correlated with that in
IOPmean in three of the above four subfields (p<0.005) and
correlation tended to be negative (p=0.07) in the superior 10° hemifield.
CONCLUSIONSDiffuse IOP related damage was
suggested in the central 30° field of NTG; greater extent of the
damage in the above four subfields was correlated with higher mean IOP.
The present findings may have clinical implications.
© 1997 by British Journal of Ophthalmology
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