Scanning laser polarimetry of the retinal nerve fibre layer in primary open angle and capsular glaucoma
a 1st Department of Ophthalmology,
Semmelweis University School of Medicine, Budapest, Hungary, b Biometry
Unit, Semmelweis University School of Medicine, Budapest, Hungary
Correspondence to: Gábor Holló, 1st Department of Ophthalmology, Semmelweis University School of Medicine, 1083 Budapest, Tömö u 25-29, Hungary.
Accepted for publication 26 June 1997
AIMS
To evaluate the clinical value of scanning
laser polarimetry with the nerve fibre analyser type II in primary open
angle glaucoma (POAG) and capsular glaucoma.
METHODS
Scanning laser polarimetry was performed
on one eye of 30 patients suffering from POAG, 25 patients suffering
from capsular glaucoma, and on 35 healthy control subjects. The retinal
nerve fibre layer (RNFL) thickness values were compared among the
groups. Reproducibility of the measurements was calculated and the
influence of pilocarpine induced miosis on the results was investigated.
RESULTS
RNFL thickness in the superior and
inferior sectors, as well as along the total circumference was
significantly lower in both glaucoma groups than in the control eyes
(p<0.05). None of the thickness values differed between the two
glaucoma groups. Reproducibility was comparable in all groups; the
coefficient of variation varied between 3.0% and 8.9% for the
different sectors investigated. Miosis had no significant impact either
on the thickness values or on the reproducibility (p>0.05).
CONCLUSION
The results suggest that scanning laser
polarimetry is a useful method for nerve fibre layer analysis in
glaucoma, and that it is not influenced by the pupil size.
© 1997 by British Journal of Ophthalmology
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