Risk of endophthalmitis after cataract extraction: results from the International Cataract Surgery Outcomes study
a Department of Social Medicine,
Faculty of Health Science, University of Copenhagen, Denmark
, b Danish Institute for Clinical Epidemiology, Copenhagen,
Denmark , c Department of
Ophthalmology, Hvidovre University Hospital, Copenhagen, Denmark
, d Worthen Center for Eye Care Research,
Georgetown University, Washington DC, USA , e Department of Health Policy and Management, Johns
Hopkins University, Baltimore MD, USA
Correspondence to: Jens Christian Norregaard, MD, Department of Social Medicine, University of Copenhagen, Blegdamsvej 3, 2200 Copenhagen N, Denmark.
Accepted for publication 16 September 1996
AIM
To estimate risk of infectious
endophthalmitis after cataract extraction in Denmark and to compare
results with the risk of this complication in the USA
METHODSIn the national Danish administrative
hospital register, 19 426 patients were identified who underwent first
eye cataract surgery from 1985 to 1987 and who were 50 years of age or
older. Of these, 61 patients had postoperative endophthalmitis.
RESULTSA 12 month cumulative risk of
rehospitalisation for endophthalmitis was estimated at 0.18% (95% CI
0.09-0.26) after extracapsular cataract extraction with lens implant.
Advanced age, male sex, intracapsular cataract extraction, and anterior
vitrectomy were all associated independently with an increased
risk of postoperative endophthalmitis. When restricting the sample to
patients aged 65 years or older, in order to allow comparisons to be
made with the US National Study of Cataract Outcomes, a 12 month risk
of 0.17% (95% CI 0.08-0.25) was estimated. The previously reported US risk of 0.12% is included in the confidence interval of the risk
estimated in the Danish sample.
CONCLUSIONDespite considerable differences in
the healthcare systems, no statistically significant difference in
outcome of surgery as measured by risk of endophthalmitis was shown
between Denmark and the USA.
© 1997 by British Journal of Ophthalmology
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