Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery
Princess Alexandra Eye Pavilion,
Edinburgh
Correspondence to: Dr M Wright, PAEP, Edinburgh EH3 9HA.
Accepted for publication 1 November 1996
AIMS
To compare the relative
anti-inflammatory potency and safety of topical
diclofenac-gentamicin with beta methasone-neomycin following
strabismus surgery.
METHODSA single centre, single observer,
prospective, randomised, and double masked clinical trial of 25 children undergoing bilateral symmetrical horizontal strabismus surgery
was carried out. One eye received diclofenac-gentamicin and the
contralateral eye received betamethasone-neomycin; both treatments
were instilled four times a day for 4 weeks postoperatively. Ocular
inflammation was assessed at 1 and 4 weeks postoperatively, objectively
by comparison with a photographic chart and subjectively by questionnaire.
RESULTSThere was no statistically significant
difference in the rate of resolution of the inflammatory response
between each group at both visits.
CONCLUSIONDiclofenac appears to be as effective
as betamethasone in controlling postoperative inflammation following
strabismus surgery and may offer a safer alternative to the use of
topical steroids.
© 1997 by British Journal of Ophthalmology
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