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British Journal of Ophthalmology 2001;85:925-927; doi:10.1136/bjo.85.8.925
Copyright © 2001 by the BMJ Publishing Group Ltd.
Br J Ophthalmol 2001;85:925-927 ( August )

Scientific correspondence

Is the pulse rate useful in assessing risk of diabetic retinopathy and macular oedema? The Wisconsin Epidemiological Study of Diabetic Retinopathy Tien Yin Wonga b c, Scot E Mossa, Ronald Kleina, Barbara E K Kleina

a Department of Ophthalmology, University of Wisconsin Medical School, Madison, Wisconsin, USA, b Department of Ophthalmology, National University of Singapore, Singapore, c Singapore National Eye Center and Singapore Eye Research Institute, Singapore

Correspondence to: Tien Yin Wong, MD, MPH, Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, 610 North Walnut Street, 460 WARF, Madison, WI 53705-2397, USA tienyinwong{at}yahoo.com

Accepted for publication 22 January 2001

AIM---To describe the relation between pulse rate and incident diabetic retinopathy.
METHODS---Population based cohort study of people with diabetes. Resting pulse rate was measured in 30 second intervals. Diabetic retinopathy was evaluated from masked gradings of fundus photographs.
RESULTS---People with higher pulse rates were more likely to have 4 year progression of retinopathy, progression to proliferative retinopathy, and incident macular oedema than those with lower pulse rates. However, these associations were attenuated after controlling for blood pressure, glycosylated haemoglobin, and other risk factors.
CONCLUSION---Pulse rate may be a clinical indicator of overall risk of diabetic retinopathy, but is not independently associated with the condition.


© 2001 by British Journal of Ophthalmology

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