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British Journal of Ophthalmology 2003;87:1229-1231; doi:10.1136/bjo.87.10.1229
Copyright © 2003 by the BMJ Publishing Group Ltd.
British Journal of Ophthalmology 2003;87:1229-1231
© 2003 BMJ Publishing Group Ltd

SCIENTIFIC REPORT

Defining and measuring treatment outcome in unilateral amblyopia

C E Stewart, M J Moseley and A R Fielder

Department of Ophthalmology, Imperial College, London, UK

Correspondence to:
Correspondence to:
Catherine Stewart, Department of Ophthalmology, Imperial College, London, 9L01, Charing Cross Hospital, St Dunstan’s Road, London W6 8RF, UK;
c.stewart{at}imperial.ac.uk

ABSTRACT

Aim: To offer a critique of current methods of defining amblyopia treatment outcome and to examine alternative approaches.

Method: Literature appraisal and descriptive case presentations.

Results: Currently, the outcome of amblyopia treatment is expressed as the number of acuity chart lines gained or, alternatively, achievement of an arbitrarily adopted level of visual acuity. As binocular vision is optimised with equal visual input from each eye the authors propose that the optimum outcome of amblyopia therapy is to achieve a visual acuity in the amblyopic eye equal to that of its fellow. In addition, improvement should be graded as the proportion of change in visual acuity with respect to the absolute potential for improvement (that is, that pertaining in the fellow eye at end of treatment).

Conclusions: There are two methods of appropriately describing the outcome of amblyopia treatment: firstly, by the difference in final visual acuity of amblyopic and fellow eye (residual amblyopia); secondly, the proportion of the deficit corrected.

Keywords: treatment outcome; unilateral amblyopia; children


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This article has been cited by other articles:

  • Stewart, C. E, Stephens, D. A, Fielder, A. R, Moseley, M. J, ROTAS Cooperative, (2007). Objectively monitored patching regimens for treatment of amblyopia: randomised trial. BMJ 335: 707-707 [Abstract] [Full Text]  
  • Stewart, C. E., Fielder, A. R., Stephens, D. A., Moseley, M. J., MOTAS Cooperative, (2005). Treatment of Unilateral Amblyopia: Factors Influencing Visual Outcome. IOVS 46: 3152-3160 [Abstract] [Full Text]  
  • Awan, M., Proudlock, F. A, Gottlob, I. (2005). A Randomized Controlled Trial of Unilateral Strabismic and Mixed Amblyopia Using Occlusion Dose Monitors to Record Compliance. IOVS 46: 1435-1439 [Abstract] [Full Text]  
  • Stewart, C. E., Moseley, M. J., Stephens, D. A., Fielder, A. R. (2004). Treatment Dose-Response in Amblyopia Therapy: The Monitored Occlusion Treatment of Amblyopia Study (MOTAS). IOVS 45: 3048-3054 [Abstract] [Full Text]  
  • O'Connor, A R, Stephenson, T J, Johnson, A, Tobin, M J, Ratib, S, Moseley, M, Fielder, A R (2004). Visual function in low birthweight children. Br. J. Ophthalmol. 88: 1149-1153 [Abstract] [Full Text]  

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