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British Journal of Ophthalmology 2004;88:1498-1499; doi:10.1136/bjo.2003.040519
Copyright © 2004 by the BMJ Publishing Group Ltd.
British Journal of Ophthalmology 2004;88:1498-1499
© 2004 BMJ Publishing Group Ltd

SCIENTIFIC REPORT

Neurological concomitants of uveitis

J R Smith and J T Rosenbaum

Casey Eye Institute, Oregon Health and Science University, Portland, OR, USA

Correspondence to:
Correspondence to:
Justine R Smith
Casey Eye Institute, Oregon Health and Science University, 3375 SW Terwilliger Blvd, Portland, OR 97239–4197, USA; smithjus{at}ohsu.edu

ABSTRACT

Aim: To describe the prevalence and types of neurological disease that occur in association with uveitis.

Methods: Retrospective review of medical records of patients attending a tertiary referral uveitis service over a 15 year period.

Results: Of 1450 patients with uveitis, 115 (7.9%) had neurological disease that was considered to be causally related to the eye inflammation. The most frequent neurological associations were Vogt-Koyanagi-Harada disease, primary central nervous system lymphoma, multiple sclerosis, and herpes virus infections.

Conclusions: Neurological disease is common among patients attending a uveitis service. The distinctive characteristics of the uveal inflammation may be useful in diagnosing the neurological disease.

Abbreviations: CNS, central nervous system; CSF, cerebrospinal fluid; MRI, magnetic resonance imaging; TNF, tumour necrosis factor; VKH, Vogt-Koyanagi-Harada

Keywords: uveitis; neurological disease; prevalence


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