EXTENDED REPORT

A newly developed peripheral anterior chamber depth analysis system: principle, accuracy, and reproducibility

K Kashiwagi, F Kashiwagi, Y Toda, K Osada, T Tsumura and S Tsukahara

Department of Ophthalmology, University of Yamanashi Faculty of Medicine, Tamaho Yamanashi, Japan

Correspondence to:
Correspondence to:
Kenji Kashiwagi MD
Department of Ophthalmology, University of Yamanashi Faculty of Medicine, 1110 Shimokato, Tamaho, Yamanashi 409-3898, Japan; kenjik{at}yamanashi.ac.jp

Aim: To develop a new, non-contact system for measuring anterior chamber depth (ACD) quantitatively, and to investigate its accuracy as well as interobserver and intraobserver reproducibility.

Methods: The system scanned the ACD from the optical axis to the limbus in approximately 0.5 second and took 21 consecutive slit lamp images at 0.4 mm intervals. A computer installed program automatically evaluated the ACD, central corneal thickness (CT), and corneal radius of curvature (CRC) instantly. A dummy eye was used for investigating measurement accuracy. The effects of CT and CRC on the measurement results were examined using a computer simulation model to minimise measurement errors. Three examiners measured the ACD in 10 normal eyes, and interobserver and intraobserver reproducibility was analysed.

Results: The ACD values measured by this system were very similar to theoretical values. Increase of CRC and decrease in CT decreased ACD and vice versa. Data calibration using evaluated CT and CRC successfully reduced measurement errors. Intraobserver and interobserver variations were small. Their coefficient variation values were 7.4% (SD 2.3%) and 6.7% (0.7%), and these values tended to increase along the distance from the optical axis.

Conclusion: The current system can measure ACD with high accuracy as well as high intraobserver and interobserver reproducibility. It has potential use in measuring ACD quantitatively and screening subjects with narrow angle.

Abbreviations: ACD, anterior chamber depth; CRC, corneal radius of curvature; CT, corneal thickness; LED, light emitting diode; PACD, peripheral anterior chamber depth; SPAC, scanning peripheral anterior chamber depth analyser; UBM, ultrasound biomicroscopy

Keywords: anterior chamber depth; angle closure glaucoma; biometry

CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    What's this?

This article has been cited by other articles:

• Wong, H.-T., Chua, J. L. L., Sakata, L. M., Wong, M. H. Y., Aung, H. T., Aung, T. (2009). Comparison of Slitlamp Optical Coherence Tomography and Scanning Peripheral Anterior Chamber Depth Analyzer to Evaluate Angle Closure in Asian Eyes. Arch Ophthalmol 127: 599-603 [Abstract] [Full Text]  
• Lavanya, R., Wong, T.-Y., Friedman, D. S., Aung, H. T., Alfred, T., Gao, H., Seah, S. K., Kashiwagi, K., Foster, P. J., Aung, T. (2008). Determinants of Angle Closure in Older Singaporeans. Arch Ophthalmol 126: 686-691 [Abstract] [Full Text]  
• Lavanya, R., Teo, L., Friedman, D. S, Aung, H. T, Baskaran, M., Gao, H., Alfred, T., Seah, S. K, Kashiwagi, K., Foster, P. J, Aung, T. (2007). Comparison of anterior chamber depth measurements using the IOLMaster, scanning peripheral anterior chamber depth analyser, and anterior segment optical coherence tomography. Br. J. Ophthalmol. 91: 1023-1026 [Abstract] [Full Text]