Article Text
Abstract
Aims: To report a prospective two centred non-comparative interventional pilot study of a solution of perfluorohexyloctane and silicone oil (Densiron-68) as a heavier than water internal tamponade.
Methods: 42 consecutive patients were recruited. The indications include proliferative vitreoretinopathy, retinal detachments arising from inferior retinal breaks, and inability to posture.
Results: The success rate with one operation using Densiron was 81% and with further surgery 93%. At the end of the study all tamponade agents were removed in 90% of patients. Visual acuity improved from mean logMAR of 1.41 (SD 0.64) to 0.94 (SD 0.57), p = 0.001. There was little evidence of dispersion and excessive inflammation.
Conclusion: This new tamponade agent is being compared to conventional silicone oil in a prospective international randomised trial.
- ERM, epiretinal membranes
- PFCL, perfluorocarbon liquids
- PPV, pars plana vitrectomy
- PVR, proliferative vitreoretinopathy
- RD, retinal detachments
- SiO, silicone oil
- perfluorohexyloctane
- silicone oil
- proliferative vitreoretinopathy
- retinal detachment
- ERM, epiretinal membranes
- PFCL, perfluorocarbon liquids
- PPV, pars plana vitrectomy
- PVR, proliferative vitreoretinopathy
- RD, retinal detachments
- SiO, silicone oil
- perfluorohexyloctane
- silicone oil
- proliferative vitreoretinopathy
- retinal detachment
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Footnotes
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↵* Deceased.
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The authors have no financial interest in the product Densiron.