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Effects of combined cataract surgery and trabeculectomy with mitomycin C on ocular dimensions

S K Law, A M Mansury, D Vasudev and J Caprioli

Jules Stein Eye Institute, University of California, Los Angeles, CA, USA

Correspondence to:
Correspondence to:
Simon K Law
MD, 100 Stein Plaza #2-235, Jules Stein Eye Institute, Los Angeles, CA 90095, USA; law{at}jsei.ucla.edu

Aims: To characterise changes in ocular dimensions after combined cataract operation and trabeculectomy with mitomycin C using separate incisions (combined operation).

Methods: 24 consecutive eyes that had combined operation and 16 eyes that had cataract operation alone were enrolled. The axial lengths before and after operations were determined with non-contact optical coherence biometry. The intraocular pressures (IOP), axial lengths, corneal curvatures, and the expected and observed refractive errors before and after operations were compared.

Results: After a combined operation, mean IOP was significantly reduced from 16.6 (SD 5.8) mm Hg to 10.9 (4.1) mm Hg (p<0.00001), and mean axial length was significantly shortened from 24.10 (0.98) mm to 23.98 (0.96) mm (p<0.00001). The mean axial length reduction after combined operation (117 (57) µm) was significantly larger than the reduction after cataract operation alone (75 (38) µm, p<0.02), and correlated significantly with the postoperative IOP (p<0.002). There was a mean with the rule surgically induced corneal astigmatism of 0.44 (0.83) dioptre by vector analysis, and a significant increase of mean keratometry reading of 0.23 (0.46) dioptre after a combined operation. However, there was no significant difference between the expected and observed refractive errors.

Conclusions: Despite an alteration of the axial length and corneal curvature, the refractive outcome after a combined operation did not differ significantly from the predicted refraction.

Abbreviations: AL, axial length; ATR, against the rule; IOL, intraocular lens; IOP, intraocular pressure; WTR, with the rule

Keywords: trabeculectomy; glaucoma; cataract; mitomycin C; axial length

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This article has been cited by other articles:

• Lin, Y-C, Kau, H-C, Kao, S-C, Hsu, W-M, Tsai, C-C (2006). Short and long term effect of combined cataract and glaucoma surgery with MMC on ocular dimensions. Br. J. Ophthalmol. 90: 250-250 [Full Text]  

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Short and long-term effect of combined cataract and glaucoma surgery with MMC on ocular dimensions

Chieh-Chih Tsai, et al.

BJO Online, 14 Nov 2005 [Full text]

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Simon K Law

BJO Online, 22 Nov 2005 [Full text]