British Journal of Ophthalmology 2007;91:476-480
CLINICAL SCIENCE-EXTENDED REPORT
Effect of the hydrophilicity of acrylic intraocular lens material and haptic angulation on anterior capsule opacification
Department of Ophthalmology, University of Vienna, Vienna, Austria
Correspondence to:
Correspondence to:
Lorenz Vock JD MD
Department of Ophthalmology, Medical University of Vienna, Währinger Gürtel 18-20, A-1090 Wien, Austria; lorenz.vock{at}meduniwien.ac.at
Aim: To evaluate the influence of hydrophilic and hydrophobic acrylic material and haptic angulation on anterior capsule opacification (ACO).
Methods: Prospective study on 53 patients with bilateral age-related cataract. Patients underwent standard cataract surgery by the same surgeon and randomly received a hydrophilic acrylic intraocular lens (IOL) in one eye and a hydrophobic acrylic IOL in the other eye. Forty five of these patients completed the one-year follow-up. The following parameters were assessed: decentration, buttonholing, anterolenticular gap (ALG), ACO, outgrowth and refractive outcome.
Results: At the one-year follow-up, ACO was seen in 80% of the hydrophilic and 100% of the hydrophobic IOLs. ACO was more intense in the hydrophobic IOLs (p<0.001). Outgrowth was seen in 42% of the hydrophilic and 2% of the hydrophobic IOLs (p = 0.0003). No case of persisting ALG was seen in the hydrophobic IOLs, but in 42% of the hydrophilic IOLs. The refractive outcome was –0.29 (SD 0.56) dioptres for the hydrophilic and 0.003 (SD 0.44) dioptres for the hydrophobic IOLs (p<0.001).
Conclusion: These results suggest that there is less ACO in hydrophilic acrylic than in hydrophobic acrylic IOLs. Although material properties might play a role, the angulated haptics of the hydrophilic IOLs exert an additional effect by the persisting ALG and a lack of contact between the IOL and the anterior capsule.
Abbreviations: ACO, anterior capsule opacification; ALG, anterolenticular gap; CCC, continuous curvilinear capsulorhexis; IOL, intraocular lens; LEC, lens epithelial cell
Keywords: acrylic intraocular lens; anterior capsule opacification; ACO; haptic angulation
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