British Journal of Ophthalmology 2008;92:351-355
ORIGINAL ARTICLES
Intravitreal bevacizumab for the treatment of macular oedema secondary to branch retinal vein occlusion
1 Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Germany
2 Department of Ophthalmology, Medical University, Innsbruck, Austria
Correspondence to:
Dr S G Priglinger, Department of Ophthalmology, Ludwig-Maximilians-University, Munich, Mathildenstr 8, 80336 Munich, Germany; siegfried.priglinger{at}med.uni-muenchen.de
Purpose: To evaluate the effect of intravitreal bevacizumab (Avastin) injections on visual acuity (VA) and foveal retinal thickness in patients with macular oedema secondary to branch retinal vein occlusion.
Methods: A prospective, non-comparative, consecutive, interventional case series of 34 patients. Patients received repeated intravitreal injections of 1.25 mg bevacizumab. Main outcome measures were VA (Snellen charts and ETDRS) and retinal thickness (optical coherence tomography measurements) in a follow-up period of 6 months.
Results: Patients presented at a mean age of 69 years (range 44–86). Mean duration of symptoms was 40 weeks (range 1–300). Mean (SD) VA at baseline was 0.79 (0.39) logMAR, improving to 0.51 (0.34) logMAR at 6 months (p = 0.009). Mean number of letters on the ETDRS chart at baseline was 45.3 (19.0), improving to 60.6 (19.9) at 6 months (p = 0.003). Mean (SD) retinal thickness at baseline was 474 (120) µm, declining to 316 (41) µm at 6 months.
Conclusion: Intravitreal injection of 1.25 mg bevacizumb appears to be an effective treatment option for branch retinal vein occlusion.
Part of this work has been presented at the 6th International Symposium on Ocular Pharmacology and Therapeutics (ISOPT), Berlin, 2006.
Competing interests: None declared.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
Relevant Article
- At a glance
- Harminder S Dua and Arun D Singh, Editors-in
Br. J. Ophthalmol. 2008 92: 301.[Extract] [Full Text] [PDF]
- Full Text
- Full Text (PDF)
-
All Versions of this Article:
bjo.2007.123513v1
92/3/351 most recent - Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in this journal
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
