Editorial
Deviant axons and glaucomatous damage
| The first 150 words of the full text of this article appear below. |
The course of ganglion cell axons from the retina to the optic
nerve is predictable and has been known accurately for over a century.
The arcuate arrangement of the axons temporally and the presence of the
median raphé were first described by the anatomists Michel1 and Dogiel2 in the latter part of
the 19th century. Vogt correctly deduced the arrangement of the
superficial nerve fibres in the retina when, in 1913, he observed the
retinal nerve fibre layer ophthalmoscopically with the aid of red-free
light.3 In contrast, the anatomical orientation of retinal
nerve fibres within the optic nerve head has been the subject of
considerable debate. Before 1930, the common view was that nerve fibres
from the peripheral retina entered the central portion of the optic nerve head.4 Loddoni established that the reverse was
true: nerve fibres from the far retina entered the peripheral optic nerve head while more central fibres occupied
Relevant Article
- Axon deviation in the human lamina cribrosa
- James E Morgan, Glen Jeffery, and Alexander J E Foss
Br. J. Ophthalmol. 1998 82: 680-683.[Abstract] [Full Text] [PDF]
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