Editorial
Brain injury and ocular motor abnormalities in surviving preterm infants
| The first 150 words of the full text of this article appear below. |
Advances in neonatal care over the past 10 years have resulted
in increased survival of very immature preterm infants but there has
not been a corresponding improvement in neurodevelopmental outcome.1 Serious neonatal morbidity is associated with
decreasing gestational age. The survival of infants of extremely low
birth weight and gestational age is associated with an increased
incidence of brain injury in the survivors. The immature central
nervous system of premature infants is particularly susceptible to
cerebrovascular damage.2-4 Intracranial, particularly
intraventricular, haemorrhage is common, especially in smaller infants
and may be associated with post-haemorrhagic hydrocephalus and with
focal infarction of the white matter. The haemorrhage arises from the
subependymal germinal matrix, a fine vascular gelatinous structure
lying beneath the ependyma of the ventricular system and containing
cells which will form mature glial cells that will later populate the
cortex.2 4 The germinal matrix is present from 10 weeks'
gestational age and has disappeared by
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Br. J. Ophthalmol. 1999 83: 514-518.[Abstract] [Full Text] [PDF]
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