Editorial
The architecture of the corneal stroma
| The first 150 words of the full text of this article appear below. |
In recent years the evolution of modern refractive surgery has focused attention on the architecture and biological properties of the cornea. In this issue of the BJO (p 437) Müller et al address the differential behaviour of the anterior and posterior stroma during corneal swelling and draw interesting conclusions about the factors maintaining corneal shape.
Transparency of the corneal stroma depends particularly on the degree of spatial order of its collagen fibrils which are narrow in diameter and closely packed in a regular array.1-8 The collagen fibrils themselves are weak scatterers, since their fibril diameter is less than the wavelength of light, and fibril refractive index is close to that of the ground substance. There is little variation in fibril diameter and separation between the anterior and posterior cornea.
The stromal fibrils are further organised into bundles,
or lamellae, of which there are approximately 300 in the central cornea and
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- The specific architecture of the anterior stroma accounts for maintenance of corneal curvature
- Linda J Müller, Elisabeth Pels, and Gijs F J M Vrensen
Br. J. Ophthalmol. 2001 85: 437-443.[Abstract] [Full Text] [PDF]
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