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In industrialised countries phacoemulsification has become a standard procedure for cataract extraction. In contrast, in developing countries while intraocular lens surgery is routinely performed, phacoemulsification is not. Nevertheless, several techniques for self sealing sutureless incisions have been developed in this setting. Hennig and coworkers describe a series of cataract patients operated on in Nepal. In this study rapid recovery of good vision could be achieved with sutureless manual extracapsular cataract extraction at a low cost in an area where high volume cataract surgery is performed. See p 266
Latanoprost, a prostaglandin, is now widely used as an antiglaucoma treatment. The mechanism of action of this drug appears to be via an increase of uveoscleral outflow by remodelling extracellular matrix and relaxation of ciliary muscle bundles. It appears that latanoprost may reduce intraocular pressure by either direct signal transduction through the FP receptor or indirect action through endogenous prostaglandins. Kashiwagi and
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