© 2003 BMJ Publishing Group
EDITORIAL
Stains in retinal surgery
Second generation vital stains in retinal surgery
UCSF Department of Ophthalmology 10 Kirkham Street, K301 San Francisco, CA 94143, USA; bhisit@itsa.ucsf.edu
Further innovations may enable novel surgical strategies
Keywords: epiretinal membrane; indocyanine green; infracyanine green; internal limiting membrane; trypan blue
| The first 150 words of the full text of this article appear below. |
In an article in this issue of the BJO by Stalmans and colleagues (p 713) and another recently by Li and colleagues,1 the novel vital stains trypan blue (TB) and infracyanine green are investigated clinically. These vital stains are promising in vitreoretinal surgery as alternatives to the by now familiar agent indocyanine green (ICG). Firstly, a brief history of membrane staining. ICG, a fluorescent dye used in choroidal angiography, was recognised for its potential in the operating room by cataract surgeons, who first used it to stain the anterior capsule to facilitate capsulorrhexis in difficult cases. Vitreoretinal surgeons, taking notice of their anterior segment colleagues’ success, soon found that ICG similarly stained the internal limiting membrane (ILM) of the retina. This was important because peeling of the nearly invisible ILM from the retinal surface had recently been advocated in macular hole surgery2,3; this was
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- Double vital staining using trypan blue and infracyanine green in macular pucker surgery
- P Stalmans, E J Feron, R Parys-Van Ginderdeuren, A Van Lommel, G R J Melles, and M Veckeneer
Br. J. Ophthalmol. 2003 87: 713-716.[Abstract] [Full Text] [PDF]
This article has been cited by other articles:
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Lee, K L, Dean, S, Guest, S
(2005). A comparison of outcomes after indocyanine green and trypan blue assisted internal limiting membrane peeling during macular hole surgery. Br. J. Ophthalmol.
89: 420-424
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