© 2005 BMJ Publishing Group Ltd
EDITORIAL
Optic nerve
Optic nerve grey crescent
Correspondence to:
Correspondence to:
Dr J B Jonas
Universitäts-Augenklinik, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim, Germany; Jost.Jonas@ma.augen.uni-heidelberg.de
Another feature in the morphological assessment of the optic nerve head
Keywords: optic disc; glaucoma; neuroretinal rim; parapapillary atrophy; grey crescent
| The first 150 words of the full text of this article appear below. |
The optic nerve head has been defined as all areas inside the peripapillary scleral ring. Outside this ring in the parapapillary region, various features and abnormalities can be differentiated. In almost all eyes, the retinal pigment epithelium shows some histological irregularities close to the tip of Bruch’s membrane at the border of the optic disc. It is the histological equivalent of the alpha zone of parapapillary atrophy which is present in almost all normal eyes. It can usually better be detected at the temporal disc margin than in other parts of the parapapillary region. The beta zone of parapapillary atrophy, present in about 25% of normal eyes, and in a higher percentage of glaucomatous eyes, reflects a complete loss of retinal pigment epithelium cells and an almost complete loss of retinal photoreceptors. Other abnormalities or changes in the parapapillary region include a hypertrophy of the retinal pigment epithelium
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