© 2005 BMJ Publishing Group Ltd
EDITORIAL
Indocyanine green
Let green lead not astray
Correspondence to:
Correspondence to:
J Sebag
MD, FACS, FRCOphth, Doheny Eye Institute, University of Southern California, and VMR Institute, 7677 Center Avenue, suite 400, Huntington Beach, CA 92647, USA; jsebag@VMRinstitute.com
Trepidations of ICG use in macular hole surgery
| The first 150 words of the full text of this article appear below. |
At the close of the 20th century the medical world was witness to a most remarkable advance when therapy was developed for a previously incurable disease. Macular hole surgery is one of the great success stories in ophthalmology, if not modern medicine. Predicated upon an increased awareness of the role of vitreous in the pathogenesis of retinal disorders, this achievement results from the work of pioneering surgeons who had the ingenuity and courage to devise and attempt a new surgical approach that now restores vision to many grateful patients. However, recent modifications of the surgical technique may jeopardise visual outcomes and "lead us astray" from early successes.
Vitreous is an extended extracellular matrix, whose molecular composition and supramolecular organisation result in a clear gel that firmly adheres to the retina in youth.1–3 Ageing induces liquefaction and vitreoretinal dehiscence, which occur concurrently in the overwhelming majority of individuals, resulting
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