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Learning with a lazy eye: a potential treatment for amblyopia
1 Visual Neuroscience Group, School of Psychology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
2 School of Optometry and Helen Wills Neuroscience Institute, UC Berkeley, Berkeley, CA 94720-2020, USA
Correspondence to:
Correspondence to:
Dr Ben Webb
University of Nottingham, University Park, Nottingham NG7 2RD, UK; bsw@psychology.nottingham.ac.uk
Accepted 2 January 2006
Keywords: amblyopia; learning
| The first 150 words of the full text of this article appear below. |
In a thought provoking editorial in the BJO, Hoyt raised two very important issues relating to the treatment of human amblyopia.1 Firstly, there is currently no effective alternative to occlusion therapy for treating amblyopia. Secondly, there is considerable "slippage" of visual acuity after cessation of occlusion therapy. Our sole purpose in responding to this editorial is to draw attention to some very recent work, showing significant long term improvements in visual performance in the adult amblyopic eye that, potentially, could be adapted for use as an effective alternative to occlusion therapy.
Visual perceptual learning—improved visual performance on a given psychophysical task after extensive training—is a well established phenomenon in the normal visual system.2 This form of learning is often tightly coupled to stimulus characteristics encoded early in visual cortex, such as the orientation or spatial frequency (size) of a visual stimulus. The stimulus specificity of perceptual improvements through training
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