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STROMAL INFLAMMATION IN CHRONIC PHASE OF OCULAR SURFACE DISEASES
Five pathological corneas, two with Stevens–Johnson syndrome (SJS), two with ocular cicatrical pemphigoid (OCP) and one with an alkali burns obtained during lamellar keratoplasty were examined histologically by immunostains and
by quantitative real-time RT–PCR to assess for stromal inflammation. Saito et al observed that number of CD34-positive cells in the stroma was decreased and the expression level of biglycan was increased in all of the pathological corneas. The expression level of MIP1a and MIP1b were also markedly increased in all corneas indicating stromal inflammation in the chronic phase of SJS, OCP and alkali burns.
See pages 10.1136/bjo.2007.127738
VEP-BASED ACUITY ASSESSMENT
In an effort to assess visual acuity (VA) estimates generated by visual evoked potentials (VEP), Bach et al subjected 40 normal subjects and 24 patients (with corneal and retinal diseases) to checkerboard stimuli with six check sizes. In normal subjects, the stimuli were optically degraded by frosted occluders. Subjective VA was obtained with
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