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Low-dose transpupillary thermotherapy versus PDT for AMD
In an effort to compare the efficacy of low-dose transpupillary thermotherapy (TTT) and PDT in patients with occult neovascular AMD, Odergren et al randomised patients to receive either low-dose TTT (and sham PDT) (n = 52) or PDT (and sham TTT) (n = 46). The primary outcome measure was the proportion of patients who lost 15 letters at 12 months. They observed that TTT and PDT were equally efficient at stabilising visual acuity, suggesting that low-dose TTT may be considered as an alternative to PDT in selected patients.
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Ethnic differences in retinal nerve fibre layer thickness
One eye of each of 137 healthy Korean subjects underwent determination of false-positive rates (FPRs) relating to retinal nerve fibre layer (RNFL) thickness parameters. Kim et al observed that the FPR for the non-nasal region was much lower than expected at <5% level. Given that the current OCT normative database is based on a largely non-Asian population, these findings
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