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British Journal of Ophthalmology 2008;92:869-870; doi:10.1136/bjo.2008.145482 Copyright © 2008 by the BMJ Publishing Group Ltd.
Stitched up: full thickness corneal graftsHarminder S Dua1, Rakesh Jayaswal1, Dalia G Said1,2
1 Division of Ophthalmology and Visual Sciences, University of Nottingham, Nottingham, UK
Correspondence to: Accepted 27 May 2008
Lamellar corneal grafts, both anterior and posterior, are rapidly taking over as procedures of choice for several indications requiring corneal transplantation. Despite the promised advantages of lamellar procedures, worldwide, penetrating keratoplasty (PK) remains the predominant procedure. In the future, even when the practice of PK diminishes, its consequences among those who have had the procedure will continue to be encountered for quite a while thereafter. Discounting primary graft failure, there are three main issues that have dogged PK ever since its inception. These are immune-mediated rejection, spherical and astigmatic refractive errors and a weak wound for the rest of the patients life. These are intricately inter-related, as interventions to deal with any one can affect the other(s). In this issue, Jeganathan et al report on a retrospective review of 947 consecutive patients who had received a PK. Of these, 5.4% required re-suturing. Individuals who required PK for microbial keratitis had
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