Article Text

PDF
Topical cyclosporine A 0.05% for recurrent anterior uveitis
  1. Shreya S Prabhu,
  2. Roni M Shtein,
  3. Monica M Michelotti,
  4. Theresa M Cooney
  1. Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, Michigan, USA
  1. Correspondence to Theresa M Cooney, Department of Ophthalmology and Visual Sciences, University of Michigan W. K. Kellogg Eye Center, 1000 Wall St, Ann Arbor, MI 48105, USA; tmnairus{at}umich.edu

Abstract

Aim To evaluate the effectiveness of treatment with cyclosporine A 0.05% eye drops in reducing frequency and severity of recurrences in patients with recurrent anterior uveitis.

Methods A retrospective case-crossover study was conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Center by one cornea specialist. We identified patients who had been treated with topical cyclosporine A 0.05% and recorded data regarding demographics, episodes of anterior uveitis, severity of episodes and treatment modalities before and after initiation of cyclosporine A 0.05%.

Results Eight patients were identified as having been treated with topical cyclosporine 0.05% in addition to standard treatment with an average follow-up of 54.9±33.9 months (range: 28–143 months). The patients had statistically significant fewer episodes of anterior uveitis, shorter duration of episodes and fewer total days of inflammation per year while on topical cyclosporine 0.05%.

Conclusions This study showed improvement of recurrent anterior uveitis in patients while on conventional treatment with cyclosporine A 0.05% compared with conventional treatment alone.

  • Treatment Medical
  • Inflammation
  • Immunology

Statistics from Altmetric.com

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Linked Articles

  • At a glance
    Keith Barton James Chodosh Jost Jonas