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Comparing optical coherence tomography findings in different etiologies of infectious necrotizing retinitis (see page 433)
Optical Coherence Tomography (OCT) findings suggestive of either Toxoplasma or Viral aetiology were identified in patients affected by necrotising retinitis. OCT signs may be useful in differentiating these entities.
Active surveillance of choroidal neovascularisation in children: incidence, aetiology and management findings from a national study in the UK (see page 438)
This prospective national surveillance study identifies the incidence (0.21 per 100 000 in age 16), aetiology, management and visual outcome in children with choroidal neovascularization. Visual prognosis was poor irrespective of CNV location and use of anti-VEGF therapy.
Optical coherence tomography angiography characterisation of Best disease and associated choroidal neovascularisation (see page 444)
Optical coherence tomography angiography reveals vascular dropout in all layers of the retina due to vitelliform lesions of Best disease. Moreover, the imaging modality is superior to fluorescein angiography in measuring choroidal neovascularization.
Changes in multiple cytokine concentrations in the aqueous humour of neovascular agerelated macular degeneration after 2 months of ranibizumab therapy (see page 448)
Aqueous humor was collected from eyes with exudative age-related macular degeneration at the initial and third ranibizumab injections. CXCL1, IP-10, CXCL12, CXCL13, MCP-1, CCL11, IL-6, and IL-10 decreased after anti-VEGF therapy. In contrast, MMP-9 increased.
Intravitreal bevacizumab monotherapy in myopic choroidal neovascularisation: 5-year outcomes for the PAN-American Collaborative Retina Study Group (see page 455)
Retrospective analysis of eyes with naïve choroidal neovascularization secondary to high myopia shows intravitreal monotherapy (IVB) is safe and effective for long-term treatment.
Neovascular age-related macular degeneration management in the third year: final results from the TREX-AMD randomised trial (see page 460)
Third year outcomes of the prospective, randomized …