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Br J Ophthalmol 1980;64:633-635 doi:10.1136/bjo.64.8.633
  • Research Article

The congenital warfarin syndrome: a case report.

  1. M. Baillie,
  2. E. D. Allen and
  3. A. R. Elkington

      Abstract

      A case is reported of a baby born with congenital abnormalities due to maternal ingestion of warfarin during pregnancy. Warfarin is known to be teratogenic, producing characteristic abnormalities, namely a hypoplastic nose, stippled epiphyses, and skeletal abnormalities. A variety of ocular abnormalities have been reported. Ophthalmologists should seek a history of maternal warfarin ingestion when seeing a baby with congenital ocular abnormalities. They should also be aware of the possible teratogenic effects when considering warfarin therapy for a woman of childbearing age.

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