The observation of changes of pial vessel calibre has withstood the test of time in assessing cerebrovascular reactivity. A recent refinement has been the adoption of the image splitting television technique of Baez, which allows accurate and rapid measurements of vessel calibre to be made in situ. This method has been successfully applied to the eye, where the retinal vessels are readily visible through the pupil. Results are presented of preliminary experiments in normal persons, in whom an induced increased in intraocular pressure was associated with retinal vasodilatation.
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