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Abnormal blood viscosity and haemostasis in long-standing retinal vein occlusion.
  1. G E Trope,
  2. G D Lowe,
  3. B M McArdle,
  4. J T Douglas,
  5. C D Forbes,
  6. C M Prentice and
  7. W S Foulds

    Abstract

    Blood viscosity and several haemostatic factors were measured in 42 patients with long-standing retinal vein occlusion and 33 control subjects. Blood viscosity, haematocrit, plasma viscosity, fibrinogen, fibrinopeptide A, and beta-thromboglobulin were increased in the 20 subjects with capillary nonperfusion or new vessels, but not in the 22 subjects without these complications. Patients with nonperfusion or new vessels also had a lower platelet count than patients without complications. Increased levels of factor VIII antigen and decreased levels of antithrombin III were found in the retinal vein occlusion group as a whole. These findings suggest that blood viscosity, platelets, and coagulation may be involved in retinal vein occlusion and its vascular complications.

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