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Br J Ophthalmol 1988;72:892-896 doi:10.1136/bjo.72.12.892
  • Research Article

Levobunolol compared with timolol: a four-year study.

  1. O Geyer,
  2. M Lazar,
  3. G D Novack,
  4. D Shen and
  5. C Y Eto
  1. Department of Ophthalmology, Ichilove Medical Center, Sackler School of Medicine, University of Tel Aviv, Israel.

      Abstract

      Fifty-one patients with raised intraocular pressure (IOP) were treated for up to four years with one of three ophthalmic solutions: 0.5% levobunolol, 1% levobunolol, or 0.5% timolol. The study was conducted as a double-masked, randomised trial in which medications were administered twice daily to both eyes. Levobunolol and timolol were equally effective in reducing overall mean IOP; reductions were greater than 8.8 mmHg in all three treatment groups. The study showed levobunolol to be as safe and effective as timolol in the long-term control of raised IOP.

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