Article Text


Ocular myasthenia gravis after D-penicillamine administration.
  1. L J Katz,
  2. R L Lesser,
  3. J R Merikangas and
  4. J P Silverman
  1. William and Anna Goldberg Glaucoma Service, Thomas Jefferson University, Philadelphia, PA 19107.


    A 68-year-old black woman who was put on D-penicillamine therapy (250-500 mg per day, total dose 15 g) for rheumatoid arthritis developed ocular myasthenia gravis. Two weeks after she discontinued D-penicillamine her signs and symptoms cleared with no other treatment. Review of previous cases and possible immunological mechanisms are discussed.

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