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Persistent superior oblique paresis as a manifestation of familial periodic cerebellar ataxia.
  1. P. G. Bain,
  2. G. B. Larkin,
  3. D. M. Calver and
  4. M. D. O'Brien
  1. Department of Neurology, UMDS, Guy's Hospital, London.

    Abstract

    A brother and sister complained of persistent diplopia due to superior oblique palsies. The cause of their symptoms became apparent when they were diagnosed as having familial periodic cerebellar ataxia (FPCA), a rare autosomal dominant condition. Oral acetazolamide (250 mg twice daily) not only prevented all the periodic symptoms but also relieved their diplopia, which had been present between attacks.

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