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Br J Ophthalmol 1997;81:846-851 doi:10.1136/bjo.81.10.846
  • Original Article
    • Clinical science

Sensitivity and specificity of optic disc variables and analysis of a new variable (MP/D) for glaucoma diagnosis with the Glaucoma-Scope

  1. Yves Lachkara,b,
  2. Howard Cohnb
  1. aGlaucoma Institute, Saint Joseph Hospital Foundation, Paris, France, bDepartment of Ophthalmology, Rothschild Eye Foundation, Paris, France
  1. Yves Lachkar, Glaucoma Institute, Saint Joseph Hospital Foundation, 3 ter rue Pierre Larousse, Paris 75014, France.
  • Accepted 26 June 1997

Abstract

AIM In an attempt to use the quantitative optic disc measurements of the Glaucoma-Scope (OIS Sacramento, CA, USA) to distinguish glaucomatous from normal optic discs, a new variable was investigated, the mean disc corrected for the disc size by dividing by the disc area: MP/D.

METHODS Glaucoma-Scope disc evaluation was performed on 81 eyes of 51 patients split into the following groups based on Humphrey 24-2 visual field and clinical criteria of glaucoma: chronic glaucoma n=27 (including only early, n=17, and low tension glaucoma, n=10), ocular hypertension n=24, pseudoglaucomatous large discs, n=12, and normal eyes, n=18. Classic optic disc variables (the vertical and horizontal c/d ratios, and the c/d area) were compared with the new MP/D index calculating receiver operating characteristic curves.

RESULTS The MP/D ratio was able to identify the glaucomatous eyes more easily than other ratios. Areas under the curves were: 0.91 (MP/D); 0.87 (c/d area); 0.85 (c/d vertical); and 0.80 (c/d horizontal). The MP/D index was also correlated with the mean deviation (r=0.466; p=0.001).

CONCLUSION MP/D may prove useful in detecting glaucomatous optic nerve damage and could be an interesting screening tool for primary open angle glaucoma.

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