Br J Ophthalmol 81:962-964 doi:10.1136/bjo.81.11.962
  • Original Article
    • Clinical science

Endogenous cortisol profile in patients with central serous chorioretinopathy

  1. S P Garg,
  2. Tanuj Dada,
  3. Dinesh Talwar,
  4. N R Biswas
  1. Dr R P Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi - 110029, India
  1. Dr T Dada.
  • Accepted 4 June 1997


AIM To study the endogenous cortisol levels in patients with central serous chorioretinopathy (CSCR).

METHODS Endogenous cortisol levels in urine and plasma were determined in 30 patients with acute CSCR and compared with 30 age and sex matched controls.

RESULTS The mean values of the 8 am plasma cortisol (29.97 μg/dl v 18.76 μg/dl), 11 pm plasma cortisol (22.03 μg/dl v 13.06 μg/dl), and 24 hour urine cortisol (11.01 mg/24 h v 7.39 mg/24 h) revealed significantly higher values in the patient group (p<0.001).

CONCLUSIONS Increased levels of endogenous cortisol are present in patients with CSCR.