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Br J Ophthalmol 1997;81:1028 doi:10.1136/bjo.81.12.1028
  • Editorial

Medical Editors Trial Amnesty (META)

  1. RICHARD SMITH
  1. Editor
  2. BMJ
  3. Child Health Monitoring Unit, Institute of Child Health, London WC1N 1EH
  4. Editor
  5. BJO
    1. IAN ROBERTS, Director
    1. Editor
    2. BMJ
    3. Child Health Monitoring Unit, Institute of Child Health, London WC1N 1EH
    4. Editor
    5. BJO
      1. JOHN V FORRESTER
      1. Editor
      2. BMJ
      3. Child Health Monitoring Unit, Institute of Child Health, London WC1N 1EH
      4. Editor
      5. BJO

          Currently over 100 medical journals around the world are inviting readers to send information on unpublished trials.150This amnesty should have important benefits for patients. Why?

          Reports of properly conducted randomised controlled trials are the foundation of effective health care, but many are not submitted for publication.12 This reduces the power of systematic reviews to detect moderate but clinically important treatment effects. Patients may thus be denied effective forms of health care. A second problem is that since trials that show more promising effects are more likely to be submitted, research syntheses …

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