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Br J Ophthalmol 81:1070-1072 doi:10.1136/bjo.81.12.1070
  • Original Article
    • Clinical science

Effects of 0.5% apraclonidine on optic nerve head and peripapillary retinal blood flow

Table 3

Volume, flow, and velocity of the optic nerve head and peripapillary retinal blood flow measured by scanning laser Doppler flowmetry (mean (SEM), n=17)

Volume Flow Velocity
AE FE AE FE AE FE
Neural rim
 baseline 19.45 (0.94) 18.48 (0.85) 454.26 (20.69) 443.15 (30.33) 1.55 (0.07) 1.55 (0.11)
 1 hour 19.27 (1.02) 20.84 (0.93) 459.81 (32.40) 481.95 (31.18) 1.59 (0.10) 1.81 (0.12)
 3 hours 18.99 (0.78) 19.31 (0.67) 462.28 (32.01) 468.42 (22.81) 1.61 (0.10) 1.73 (0.08)
Peripapillary retina
baseline 19.59 (0.72) 19.08 (0.88) 354.28 (21.01) 340.78 (19.38) 1.22 (0.07) 1.18 (0.06)
 1 hour 19.75 (1.71) 19.15 (0.95) 359.88 (18.29) 346.68 (22.14) 1.23 (0.06) 1.19 (0.07)
 3 hours 19.48 (0.07) 19.79 (0.97) 355.23 (28.99) 377.80 (18.00) 1.27 (0.09) 1.25 (0.09)
  • No significant changes from the baseline values in either AE (p >0.4) or FE (p >0.2).

  • No significant differences between AE and FE at each time point (p >0.1).

  • AE = apraclonidine treated eyes; FE = fellow eyes.

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