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Br J Ophthalmol 81:1099-1106 doi:10.1136/bjo.81.12.1099
  • Original Article
    • Laboratory science

Adhesion molecules in vernal keratoconjunctivitis

Table 3

Distribution of adhesion molecules in normal conjunctiva and conjunctiva from patients with VKC

Adhesion molecule Normal conjunctiva (n=4) VKC (n=14)
EPC VEC MC EPC VEC MC
ICAM-1 + +++ +++ ++
ICAM-3 + +++
LFA-1 + +++
VLA-4 + ++
VCAM-1 +
ELAM-1 +
  • VKC = vernal keratoconjunctivitis; EPC = epithelial cells; VEC = vascular endothelial cells; MC = mononuclear cells; ICAM-1 = intercellular adhesion molecule-1; ICAM-3 = intercellular adhesion molecule-3; LFA-1 = lymphocyte function associated antigen-1; VLA-4 = very late activation antigen-4; VCAM-1 = vascular cell adhesion molecule-1; ELAM-1 = endothelial leucocyte adhesion molecule-1.

  • Basal epithelium. (− no cells stain; + few cells stain; ++ moderate number of cells stain; +++ nearly all cells stain).

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