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Br J Ophthalmol 81:308-313 doi:10.1136/bjo.81.4.308
  • Original Article
    • Laboratory science

Detection of human papillomavirus infection in squamous tumours of the conjunctiva and lacrimal sac by immunohistochemistry, in situ hybridisation, and polymerase chain reaction

Table 1

Clinicopathological data and results of human papillomavirus (HPV) analysis

Patient no, age (years), sex Site Histology Koilocytosis Immunohistochemistry In situ hybridisation PCR
1, 20, M Bulbar and palpebral conj (bilateral) Benign + + Broad spectrum and type 6 Type 6
2, 26, M Bulbar conj Benign
3, 35, M Palpebral conj (bilateral) Benign
4, 47, M Palpebral conj Benign + + Type 6
5, 50, M Lacrimal sac Benign
6, 67, M Corneal limbus Benign + + Broad spectrum and type 6 Type 6
7, 68, F Palpebral conj Benign
8, 73, M Bulbar conj Benign
9, 73, F Bulbar conj Benign + + Type 6
10, 70, M Corneal limbus Moderate dysplasia + + Broad spectrum Type 16
11, 26, F Lacrimal sac Severe dysplasia + + Broad spectrum and type 16 Type 16
12, 59, F Bulbar conj Severe dysplasia
13, 63, M Corneal limbus Severe dysplasia + + Broad spectrum and type 18 Type 18
14, 44, M Bulbar conj Ca in situ + Type 18
15, 72, M Bulbar conj Ca in situ
16, 56, M Bulbar conj Squamous cell ca
17, 74, M Bulbar conj Squamous cell ca
  • PCR = polymerase chain reaction; conj = conjunctiva; ca = carcinoma.

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