Table 2
Renal and ocular features of patients with IgA glomerulonephritis or Alport syndrome
| (A) IgA glomerulonephritis | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Patient | Sex | Age | Haem | Pro | BP | Renal function | Cornea | Lens | Retina |
| JJ | F | 37 | + | + | ABN | N | N | N | 0 dots |
| LJ | F | 64 | + | + | N | N | dots | N | 0 dots |
| JB | M | 58 | + | + | N | ABN | N | N | 100 dots |
| JM | M | 39 | + | + | N | N | N | N | 0 dots |
| FE | F | 46 | + | + | N | ABN | N | N | 0 dots |
| FD | F | 38 | − | − | N | N | N | N | 0 dots |
| CL | M | 23 | + | − | N | N | N | N | 0 dots |
| HP | M | 51 | + | − | N | N | N | N | 0 dots |
| TW | M | 51 | + | + | N | ABN | N | N | 0 dots |
| GJ | M | 44 | + | + | ABN | ABN | N | N | 1 dot |
| FR | F | No further details | N | N | 0.5 dots | ||||
| (B) X linked Alport syndrome | |||||||||
| Patient | Sex | Age (years) | FH | Hearing | Renal function | Age at renal failure | Cornea | Lens | Retina |
| DH | M | 17 | + | Abn | N, haem | NA | Corneal dystrophy | Dots | 1 dot |
| PH | F | 45 | + | N | N, haem | NA | Corneal dystrophy | N | 0.5 dot |
| JT | F | 46 | + | N | N, haem | NA | N | Opacity | 6 dots |
| NH | M | 30 | − | Abn | Transplant | 15 | Dots | Scissor’s reflex | Dots and flecks |
| AC | M | 34 | − | Abn | Transplant | 17 | N | N | Dots and flecks |
| CH | F | 37 | + | N | N, haem | NA | N | N | 1 dot |
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Haem = + RBC greater than × 106/l; Pro = proteinuria + more than 0.3 g/day; BP + = blood pressure more than 140/90 mm Hg; FH = family history; N = normal; Abn = abnormal; NA = not applicable.
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↵PH and DH are mother and son; electron microscopy of PH’s renal biopsy was typical of Alport syndrome, but DH has not had a biopsy.
