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Br J Ophthalmol 1997;81:421 doi:10.1136/bjo.81.5.421c
  • Correspondence

A case of Leber's hereditary optic neuropathy with elevated blood levels of lactate and pyruvate

  1. TSUTOMU NINOMIYA,
  2. HIROKO YAMAZAKI
  1. Department of Ophthalmology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan
  2. Department of Ophthalmology, School of Medicine, Chiba University, Japan
  3. Department of Neurology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan
    1. SHIN MUNAKATA
    1. Department of Ophthalmology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan
    2. Department of Ophthalmology, School of Medicine, Chiba University, Japan
    3. Department of Neurology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan
      1. HIIDE YOSHINO,
      2. TAKESHI SATO
      1. Department of Ophthalmology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan
      2. Department of Ophthalmology, School of Medicine, Chiba University, Japan
      3. Department of Neurology, Kohnodai Hospital, National Center of Neurology and Psychiatry, Japan

          Editor,—Leber's hereditary optic neuropathy (LHON) is a maternally inherited disease characterised by acute bilateral loss of central vision.1 We report a patient with LHON who had elevated lactate and pyruvate levels in blood and cerebrospinal fluid (CSF).

          CASE REPORT

          A 22-year-old man noticed blurred vision in both his eyes. Corrected visual acuity was 0.04 in his right eye and 0.05 in his left. Slit-lamp examination and intraocular pressures were normal. Pupillary light reflex …

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