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Br J Ophthalmol 82:1199-1202 doi:10.1136/bjo.82.10.1199
  • Original Article
    • Laboratory science

Possible role for nitric oxide releasing nerves in the regulation of ocular blood flow in the rat

Table 1

Effects of 7-NI and L-NAME upon physiological measurements

Physiological variables Treatment
Oil 7-NI Saline L-NAME
Ocular blood flow (ml/100 g/min) 85 (2) 59 (7)* 84 (8) 35 (4)*
Ocular vascular resistance (mm Hg/ml/100 g/min) 1.54 (0.06) 2.46 (0.28)* 1.50 (0.05) 4.40 (0.31)*
Pco 2(mm Hg) 39.6 (3.0) 42.1 (1.5) 42.0 (3.4) 41.2 (2.1)
Po2 (mm Hg) 94.1 (3.0) 92.4 (4.1) 96.7 (5.1) 96.9 (5.2)
pH 7.40 (0.03) 7.39 (0.03) 7.43 (0.02) 7.41 (0.04)
MABP (mm Hg) 128 (7) 133 (7) 125 (5) 156 (3)*
Heart rate (beats/min) 442 (43) 317 (18)* 440 (40) 276 (41)*
No 4 5 5 5
  • All data are presented as mean (SD) *Significantly different from appropriate control group, p<0.05, Scheffé test.

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