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Br J Ophthalmol 82:1329-1334 doi:10.1136/bjo.82.11.1329
  • Original Article
    • Laboratory science

Accumulation of tissue inhibitor of metalloproteinases-3 in human eyes with Sorsby’s fundus dystrophy or retinitis pigmentosa

Table 1

Characteristics of human retinas used in study

Reference No Age (years) Fixative Postmortem time (hours) Diagnosis
0770-95 83 P 6 Normal
1481-93 85 P/G 7 Normal
SFD-35-97 (RE) 77 F/G 20 SFD
SFD-36-97 (LE) 77 F 20 SFD
FFB-316 68 P/G 8.5 RP
FFB-356 80 P/G 5 RP
FFB-516 81 P/G 2 RP
  • F=formalin; P=4% paraformaldehyde; G=0.5% glutaraldehyde; SFD=Sorsby’s fundus dystrophy; FFB=Foundation Fighting Blindness; RP=retinitis pigmentosa.

  • Autosomal dominant RP caused by rhodopsin Thr-17-Met mutation.27

  • Autosomal dominant RP with thick subretinal pigment epithelium deposits.23

  • Autosomal dominant RP, genotype unknown.

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