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Br J Ophthalmol 82:498-503 doi:10.1136/bjo.82.5.498
  • Original Article
    • Clinical science

Plasma endothelin-1 concentrations in patients with retinal vein occlusions

Table 1

Clinical and laboratory findings

Patient No Occlusion type Age (years)/sex ET-1 levels (pg/ml) Systemic hypertension (+/−) Ocular hypertension (+/−)
Group A, RVO patients (n = 18): 14.22 (4.6)
Group A1: NIT RVO (n = 11) 12.46 (4.3)
 1 BRVO 57/M 5.6 +
 2 BRVO 64/F 10.3 +
 3 BRVO 65/M 18.3 +
 4 BRVO 66/F 8.7 +
 5 BRVO 66/M 12.6
 6 BRVO 73/M 13.5
 7 CRVO 41/M 9.0
 8 CRVO 52/M 14.1 +
 9 CRVO 63/F 14.4 +
 10 CRVO 72/F 10.2 + +
 11 CRVO 74/F 20.4 + +
Group A2: IT RVO (n = 7) 16.97 (3.5)
 12 BRVO 62/M 18.4 +
 13 BRVO 67/M 13.7 −()
 14 BRVO 68/M 14.2 + −()
 15 CRVO 54/F 18.3 + +
 16 CRVO 58/M 16.2 +
 17 CRVO 68/M 24.2 + +
 18 CRVO 70/F 13.8 +
Group B, Normal subjects (n=20) 7.90 (1.6)
Group C, Uncomplicated hypertensives (n=15) 8.50 (2.9)
  • NIT RVO = non-ischaemic type retinal vein occlusions; IT RVO = ischaemic type retinal vein occlusions; BRVO = branch retinal vein occlusions; CRVO = central retinal vein occlusions.

  • Mean (SD).

  • p Value <0.05 for group A and A1 v groups B and C, respectively, and for group A2 v group A1.

  • p Value <0.01 for group A2 v groups B and C, respectively.

  • Patients with neovascular glaucoma at the time of diagnosis and blood sampling.

  • Bilateral anterior chamber angle narrowing upon examination.

  • History of borderline intraocular pressure (range 18–20 mm Hg).

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