Retinoblastoma associated orbital cellulitis

Table 2

Extent of tumour spread in 12 patients with retinoblastoma associated cellulitis, based on histopathological findings

Case no	Corneal invasion	Tumour cells in anterior chamber	Iris invasion	Trabecular meshwork involvement	Ciliary body invasion	Choroidal invasion	Tumour cells in emissary channels	Optic nerve invasion	Extrascleral extension
1	—	yes	—	yes	yes	3+	—	3+	—
2	—	yes	—	—	—	1+	—	1+	—
3	—	yes	—	yes	yes	3+	—	—	—
5	—	yes	yes	yes	yes	3+	—	1+	—
6	—	yes	—	—	yes	3+	—	2+	—
7	—	—	—	—	—	—	—	—	—
8	—	—	—	yes	yes	3+	—	3+	—
9	—	yes	—	—	—	—	—	—	—
10	—	—	—	—	yes	—	—	—	—
12	yes	yes	yes	yes	yes	3+	yes	—	yes
13	—	—	—	—	—	2+	—	—	—
14	—	yes	yes	yes	—	3+	yes	3+	yes

↵Patients 4 and 11 not enucleated therefore not included.
↵Polymorphonucleocytes in AC.

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Case no	Corneal invasion	Tumour cells in anterior chamber	Iris invasion	Trabecular meshwork involvement	Ciliary body invasion	Choroidal invasion	Tumour cells in emissary channels	Optic nerve invasion	Extrascleral extension
1	—	yes	—	yes	yes	3+	—	3+	—
2	—	yes	—	—	—	1+	—	1+	—
3	—	yes	—	yes	yes	3+	—	—	—
5	—	yes	yes	yes	yes	3+	—	1+	—
6	—	yes	—	—	yes	3+	—	2+	—
7	—	—	—	—	—	—	—	—	—
8	—	—	—	yes	yes	3+	—	3+	—
9	—	yes	—	—	—	—	—	—	—
10	—	—	—	—	yes	—	—	—	—
12	yes	yes	yes	yes	yes	3+	yes	—	yes
13	—	—	—	—	—	2+	—	—	—
14	—	yes	yes	yes	—	3+	yes	3+	yes

Case no	Corneal invasion	Tumour cells in anterior chamber	Iris invasion	Trabecular meshwork involvement	Ciliary body invasion	Choroidal invasion	Tumour cells in emissary channels	Optic nerve invasion	Extrascleral extension
1	—	yes	—	yes	yes	3+	—	3+	—
2	—	yes	—	—	—	1+	—	1+	—
3	—	yes	—	yes	yes	3+	—	—	—
5	—	yes	yes	yes	yes	3+	—	1+	—
6	—	yes	—	—	yes	3+	—	2+	—
7	—	—	—	—	—	—	—	—	—
8	—	—	—	yes	yes	3+	—	3+	—
9	—	yes	—	—	—	—	—	—	—
10	—	—	—	—	yes	—	—	—	—
12	yes	yes	yes	yes	yes	3+	yes	—	yes
13	—	—	—	—	—	2+	—	—	—
14	—	yes	yes	yes	—	3+	yes	3+	yes

Retinoblastoma associated orbital cellulitis

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Case no	Corneal invasion	Tumour cells in anterior chamber	Iris invasion	Trabecular meshwork involvement	Ciliary body invasion	Choroidal invasion	Tumour cells in emissary channels	Optic nerve invasion	Extrascleral extension
1	—	yes	—	yes	yes	3+	—	3+	—
2	—	yes	—	—	—	1+	—	1+	—
3	—	yes	—	yes	yes	3+	—	—	—
5	—	yes	yes	yes	yes	3+	—	1+	—
6	—	yes	—	—	yes	3+	—	2+	—
7	—	—	—	—	—	—	—	—	—
8	—	—	—	yes	yes	3+	—	3+	—
9	—	yes	—	—	—	—	—	—	—
10	—	—	—	—	yes	—	—	—	—
12	yes	yes	yes	yes	yes	3+	yes	—	yes
13	—	—	—	—	—	2+	—	—	—
14	—	yes	yes	yes	—	3+	yes	3+	yes