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Br J Ophthalmol 82:743-747 doi:10.1136/bjo.82.7.743
  • Original Article
    • Clinical science

Bilateral involvement by age related maculopathy lesions in a population

Table 3

Effect of sex on the frequency of bilateral involvement by age related macular degeneration (AMD) and age related maculopathy (ARM) lesions

Outcomes Female Male Multivariate adjusted odds ratio (95% CI)
Total cases No of bilateral (%) Total cases No of bilateral (%)
Any ARM 139 116  (83) 91 67  (74) 1.6  (0.8–3.2)
Any AMD 47 30 (64) 22 9 (41) 2.5 (0.8–8.0)
 neovascular AMD 33 17 (52) 15 2 (13) 7.7 (1.3–46.7)
 geographic atrophy 25 16 (64) 14 6 (43) 2.4 (0.6–10.0)
Any early ARM 92 74 (80) 69 49 (71) 1.6 (0.7–3.5)
 reticular drusen 25 24 (96) 10 8 (80) 8.5 (0.5–133.1)
 indistinct soft  drusen 63 50 (79) 55 43 (78) 1.0 (0.4–2.6)
 distinct soft drusen 104 51 (49) 80 36 (45) 1.1 (0.6–2.0)
 pigmentary  abnormality 190 78 (41) 184 62 (34) 1.3 (0.8–1.9)
 hyperpigmentation 186 77 (41) 182 61 (34) 1.3 (0.8–2.0)
 hypopigmentation 141 44 (31) 121 29 (24) 1.4 (0.8–2.5)
  • Adjusted for age, family history of AMD and current smoking.

  • Adjusted for age and current smoking only as no unilateral cases had a family history of AMD.

  • Adjusted for age only as no unilateral cases had a family history of AMD or currently smoked.

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