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Br J Ophthalmol 82:875-879 doi:10.1136/bjo.82.8.875
  • Original Article
    • Clinical science

Optic disc morphology in pigmentary glaucoma

Table 2

Measurements of the optic disc and intraocular pressure (mean (SD))

Pigmentary glaucoma Primary open angle glaucoma p Value Primary open angle glaucoma adjusted for refractive error and age p Value
n 62 566 102
Optic disc area (mm2) 2.67  (0.79) 2.69  (0.62) 0.21  (ns) 2.67  (0.72) 0.55  (ns)
Min/max diameter 0.87 (0.07) 0.89 (0.07) 0.007   0.89 (0.07) 0.06 (ns)
Form factor 0.97 (0.02) 0.97 (0.06) 0.84 (ns) 0.97 (0.02) 0.83 (ns)
Rim area (mm2):
 Total 1.18 (0.48) 1.16 (0.37) 0.45 (ns) 1.25 (0.39) 0.35 (ns)
 Temporal horizontal 0.17 (0.09) 0.17 (0.08) 0.30 (ns) 0.18 (0.08) 0.95 (ns)
 Temporal superior 0.30 (0.15) 0.29 (0.11) 0.59 (ns) 0.31 (0.12) 0.67 (ns)
 Temporal inferior 0.29 (0.14) 0.30 (0.12) 0.64 (ns) 0.34 (0.13) 0.67 (ns)
 Nasal 0.44 (0.17) 0.42 (0.13) 0.31 (ns) 0.45 (0.15) 0.02 (ns)
Rim width (mm):
 Temporal 0.20 (0.15) 0.19 (0.10) 0.33 (ns) 0.20 (0.11) 0.75 (ns)
 Inferior 0.26 (0.18) 0.26 (0.13) 0.48 (ns) 0.29 (0.12) 0.30 (ns)
 Nasal 0.29 (0.16) 0.28 (0.11) 0.18 (ns) 0.30 (0.11) 0.85 (ns)
 Superior 0.29 (0.19) 0.26 (0.12) 0.11 (ns) 0.29 (0.14) 0.81 (ns)
Cup/disc diameter ratios:
 Horizontal 0.71 (0.16) 0.73 (0.12) 0.35 (ns) 0.71 (0.14) 0.76 (ns)
 Vertical 0.71 (0.17) 0.73 (0.14) 0.51 (ns) 0.69 (0.15) 0.34 (ns)
 Horizontal/vertical 1.00 (0.09) 1.02 (0.11) 0.47 (ns) 1.03 (0.09) 0.02
Optic cup depth (relative units) 2.4 (0.9) 2.6 (0.9) 0.08 (ns) 2.5 (1.0) 0.27 (ns)
Frequency of disc haemorrhages 3.2% 6.2% >0.05 (ns) 2.9% >0.05 (ns)
Localised retinal nerve fibre layer defects 16% 22% >0.05 (ns) 19% >0.05 (ns)
Alpha zone area (mm2):
 Total 0.68 (0.57) 0.72 (0.59) 0.63 (ns) 0.81 (0.60) 0.19 (ns)
 Temporal horizontal 0.32 (0.26) 0.33 (0.24) 0.53 (ns) 0.36 (0.25) 0.20 (ns)
 Temporal superior 0.11 (0.11) 0.15 (0.16) 0.17 (ns) 0.18 (0.20) 0.06 (ns)
 Temporal inferior 0.18 (0.15) 0.16 (0.18) 0.20 (ns) 0.17 (0.14) 0.86 (ns)
 Nasal 0.07 (0.20) 0.09 (0.18) 0.20 (ns) 0.10 (0.18) 0.24 (ns)
Beta zone area (mm2):
 Total 0.52 (0.71) 0.60 (1.09) 0.75 (ns) 0.52 (0.77) 0.77 (ns)
 Temporal horizontal 0.22 (0.25) 0.21 (0.33) 0.36 (ns) 0.22 (0.16) 0.94 (ns)
 Temporal superior 0.10 (0.25) 0.11 (0.21) 0.64 (ns) 0.11 (0.20) 0.46 (ns)
 Temporal inferior 0.17 (0.29) 0.16 (0.31) 0.38 (ns) 0.13 (0.21) 0.43 (ns)
 Nasal 0.04 (0.11) 0.12 (0.39) 0.30 (ns) 0.07 (0.26) 0.73 (ns)
Retinal vessel diameter (mm), arteriole:
 Temporal inferior 0.093 (0.032) 0.102 (0.029) 0.19 (ns) 0.103 (0.023) 0.05 (ns)
 Temporal superior 0.098 (0.028) 0.098 (0.024) 0.59 (ns) 0.101 (0.026) 0.54 (ns)
 Nasal superior 0.091 (0.030) 0.090 (0.024) 0.31 (ns) 0.095 (0.023) 0.64 (ns)
 Nasal inferior 0.093 (0.031) 0.091 (0.027) 0.44 (ns) 0.093 (0.024) 0.15 (ns)
Venule:
 Temporal inferior 0.127 (0.037) 0.138 (0.033) 0.09 (ns) 0.139 (0.035) 0.07 (ns)
 Temporal superior 0.131 (0.040) 0.132 (0.032) 0.62 (ns) 0.133 (0.032) 0.84 (ns)
 Nasal superior 0.113 (0.038) 0.113 (0.033) 0.75 (ns) 0.111 (0.031) 0.31 (ns)
 Nasal inferior 0.124 (0.035) 0.113 (0.033) 0.09 (ns) 0.117 (0.031) 0.88 (ns)
Perimetric loss variance value (dB2) 19.97 (30.6) 20.7 (24.99) 0.34 (ns) 16.2 (23.0) 0.35 (ns)
Intraocular pressure (mm Hg):
 Mean maximal 24.5 (6.6) 21.2 (5.1) <0.0001 22.0 (5.1) 0.0008
 Mean minimal 13.0 (2.8) 13.2 (3.0) 0.73 (ns) 13.9 (3.0) 0.10 (ns)
 Amplitude 11.5 (6.6) 8.0 (5.2) <0.0001 7.9 (5.3) 0.0008
  • p Value = significance of differences between the pigmentary glaucoma group and the primary open angle glaucoma group adjusted or not adjusted for age and refractive error; ns = statistically not significant.

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