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Br J Ophthalmol 82:916-918 doi:10.1136/bjo.82.8.916
  • Original Article
    • Clinical science

Anti-GQ1b ganglioside antibody and ophthalmoplegia of undetermined cause

Table 1

Patients with ophthalmoplegia of undetermined cause

Patient No Age (years ) Sex Pattern of palsy Anti-GQlb IgG antibody titre Steroid treatment Period for recovery Neurological signs Neuroimaging study
1 24 F R, VI <10 + 4 m R, proptosis CT, MRI
2 64 M L, VI <10 + 3 m CT
3 56 M L, VI <10 2 w
4 52 F B, total <10 + 1 y CT, MRI
5 47 M R, So <10 + 3 m
6 73 F B, VI <10 2 m ataxic gait CT
7 40 M B, VI <10 + 3 w CT, MRI
8 62 F R, total 20 + 3 m CT
9 51 M R, VI <10 + 4 m CT, MRI
10 45 M R, total <10 + 4 m R, proptosis CT
11 57 M L, VI <10 + 6 m decreased reflex CT
12 69 M L, So <10 4 m CT
13 56 F B, VI 640 + 2 m areflexia CT
14 37 M GPN <10 1 m CT, MRI
15 40 F L, So <10 + 4 m MRI
16 61 M R, total+L, VI <10 4 m CT
  • B = bilateral; VI = abducens palsy; total = total ophthalmoplegia; Sr = superior rectus muscle palsy; So = superior oblique muscle palsy; GPN = gaze paretic nystagmus; m = month(s), w = week(s), y = year(s); CT = head CT scan; MRI = magnetic resonance imaging.

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