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Br J Ophthalmol 82:1033-1038 doi:10.1136/bjo.82.9.1033
  • Original Article
    • Clinical science

Anti-Acanthamoeba activity of contact lens solutions

Table 2

Contact lens solutions tested

Solution trade name Manufacturer Active ingredient(s) Preservative(s) Type(s) of lens
Bausch & Lomb Multi-Purpose Solution Bausch & Lomb Polyaminopropyl biguanide (Dymed) (0.0005); 0.11% (wt/vol) Disodium edetate Soft
sodium borate (1.20);
sodium chloride (4.9);
poloxamine 1107 (10.00);
boric acid (6.40)
Complete Allergan Polyhexamethylene biguanide (0.001) Soft
Duracare Allergan 0.004% Polyvinyl alcohol 0.004% Benzalkonium chloride; Gas permeable
0.004% Sodium edetate
Hydrocare Cleaning/Soaking Solution Allergan Alkyl triethanol ammonium chloride (0.3) 0.002% Thiomersal Soft
Optifree Alcon 0.001% m/v Polyquad (polyquaternium-1); Soft
0.05% (wt/vol) sodium edetate
Optisoak Alcon 0.75 g polyvinyl alcohol;
0.005 g polysorbate 80;
0.65 g hydroxyethyl cellulose
(all per 100 ml)
+ sodium chloride
+ sodium phosphates
Polyquad, ie polyquaternium-1 0.005% (wt/vol);
edetate sodium 0.1% (wt/vol)
Gas permeable and hard
Oxysept 1 Allergan Hydrogen peroxide (31.0) Soft
Oxysept 1 Step Allergan 3% Hydrogen peroxide Soft
Total Allergan Polyvinyl alcohol (25.0) 0.004% benzalkonium chloride Gas permeable and hard
Transoak Chauvin Pharmaceuticals Ltd 0.01% (wt/vol) benzalkonium chloride 0.2% (wt/vol) disodium edetate Gas permeable and hard
Transol Wetting Solution Chauvin Pharmaceuticals Ltd 1 g polyvinyl alcohol/50 ml 0.004% benzalkonium chloride; Gas permeable and hard
0.02% (wt/vol)disodium edetate
  • All data in parentheses are in mg/ml.

  • Minimum stated soaking period for solution is 4 hours.

  • Minimum stated soaking period for solution is overnight (one manufacturer states that this is approximately 6–8 hours).

  • Minimum stated soaking period for solution is 20 minutes.

  • Minimum stated soaking period for solution is 2 hours.

  • Minimum soaking period not stated.

  • Minimum soaking period is not stated as this is a wetting solution, not intended for soaking lenses.It was included as its constituents are similar to those of other soaking solutions tested, but it is manufactured by a different company.

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