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Br J Ophthalmol 83:54-61 doi:10.1136/bjo.83.1.54
  • Original Article
    • Clinical science

Quantitative assessment of macular thickness in normal subjects and patients with diabetic retinopathy by scanning retinal thickness analyser

Table 3

Average macular thicknesses in the study groups

Group Central macular thickness (μm) Mean (SD) Range (μm) p Value
Normal eyes (n=40) 182 (16) 164–221
Eyes with diabetic retinopathy (n=60)
CSMO detection by slit lamp biomicroscopy
 non-CSMO (n=24) 283 (116) 156–423 0.019
 CSMO (n=36) 564 (168) 278–906 <0.001
Leakage grading using fluorescein angiography
 None (n=10) 187 (76) 156–328 0.597
 Questionable leakage (n=11) 191 (151) 146–388 0.678
 Focal leakage (n=18) 320 (146) 181–562 0.069
 Diffuse leakage (n=21) 552 (166) 324–906 0.022
  • Central macular thickness compared with normal subjects. Statistical analysis was done using the unpaired Mann-Whitney U test.

  • Central macular thickness was measured using the scanning retinal thickness analyser.

  • CSMO = clinically significant macular oedema.

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