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Br J Ophthalmol 83:1121-1124 doi:10.1136/bjo.83.10.1121
  • Original Article
    • Clinical science

Double blind, randomised, placebo controlled, crossover, multicentre study to determine the efficacy of a 0.1% (w/v) sodium hyaluronate solution (Fermavisc) in the treatment of dry eye syndrome

Table 5

Results from rose bengal test (total score) in crossover phase

HA→saline (SD) saline→HA (SD)
Left eye:
 1st period 3.4  (1.3) 4.4  (2.1)
 2nd period 4.3 (1.8) 3.3 (1.7)
 1st–2nd −1.0 (1.6) 1.1 (2.1)
Treatment difference test: t=4.5, p=0.0001
Left eye:
 1st period 3.5 (1.1) 4.4 (2.2)
 2nd period 4.3 (1.8) 3.4 (1.4)
 1st–2nd −0.8 (1.4) 1.1 (2.2)
Treatment difference test: t=4.3, p=0.0001
Combined test on sum from both eyes: t=4.7, p=0.0001

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